Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC450H711N129O142S2

DescriptionStandard

        ELTGERLEQARGPEAQAESAAARAELEYGLVAEAEAEAAEKKDSGPYKMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
    

Molecular Weight10264.37 Da

Isoelectric Point (pI)7.04

Net Charge (pH 7.0)0.03

Net Charge (pH 7.4) -0.28

Charge Density (pH 7.0) 0.0004

GRAVY Index-0.93

Hydrophobic Moment 0.49

Boman Index-0.16

Instability Index31.15

Aliphatic Index 54.84

Aromaticity 0.0753

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4400.22

LogP -46.63

H-bond Donors 150.0

H-bond Acceptors 146.0

Rotatable Bonds 350.0

Heavy Atoms 723.0

Ring Count 15.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218603 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0285567 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyPOMC

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsTyr28 Sulfotyrosine

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0373178 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLipotropin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods28:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour