Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC516H850N128O146S2

DescriptionStandard

        MNLVKSNKKSFILFGVALAAATLVYALLLTGTELNVAAAHAFSANAELASTLGISTAAAKKAIDIIDAASTIASIISLIGIVTGAGAISYAIVATAKTMIKKYGKKYAAAW
    

Molecular Weight11247.17 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)5.58

Net Charge (pH 7.4) 5.29

Charge Density (pH 7.0) 0.0503

GRAVY Index0.84

Hydrophobic Moment 0.56

Boman Index0.35

Instability Index10.27

Aliphatic Index 124.32

Aromaticity 0.0721

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4335.61

LogP -38.73

H-bond Donors 154.0

H-bond Acceptors 155.0

Rotatable Bonds 375.0

Heavy Atoms 792.0

Ring Count 10.0

Amide Bonds 114.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377471 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus velezensis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal