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MYP_041717
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Basic Information
Dolabellanin B2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
33 amino acids
C163H248N48O48S7
Standard
Sequence
SHQDCYEALHKCMASHSKPFSCSMKFHMCLQQQ
Physicochemical Analysis
3872.46 Da
7.71
0.77
0.29
0.0233
-0.60
0.48
-0.09
74.86
29.70
0.0909
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1546.85
-17.42
56.0
60.0
129.0
266.0
8.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0343948 VERIFIED: YES
Provenance & Taxonomy
Dolabella auricularia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Schizosaccharomyces pombe
PMID12590964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12590964/
RECORD: Rec_0345225 VERIFIED: YES
Provenance & Taxonomy
Dolabella auricularia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis
PMID12590964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12590964/
RECORD: Rec_0355714 VERIFIED: YES
Provenance & Taxonomy
Dolabella auricularia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0362798 VERIFIED: YES
Provenance & Taxonomy
Dolabella auricularia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli
PMID12590964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12590964/
RECORD: Rec_0367255 VERIFIED: YES
Provenance & Taxonomy
Dolabella auricularia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Toxicity
Bacillus subtilis
5 μg/mL
LC50
PaperA novel antimicrobial peptide from the sea hare Dolabella auricularia
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