Peptide Database

Peptide NameCycloviolacin VY1

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC120H197N33O38S6

DescriptionStandard

        CAESCVYIPCLTSAIGCSCKSKVCYRN
    

Molecular Weight2902.44 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0629

GRAVY Index0.44

Hydrophobic Moment 0.32

Boman Index0.08

Instability Index33.76

Aliphatic Index 72.22

Aromaticity 0.0741

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1147.07

LogP -14.28

H-bond Donors 47.0

H-bond Acceptors 46.0

Rotatable Bonds 92.0

Heavy Atoms 197.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307351 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)