Peptide Database

Peptide NameM8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC187H319N55O43

DescriptionStandard

        KWKLFKKIHKVGQNIRKGIIKAGPAVAVVGQATQIAK
    

Molecular Weight4025.88 Da

Isoelectric Point (pI)11.51

Net Charge (pH 7.0)8.84

Net Charge (pH 7.4) 8.57

Charge Density (pH 7.0) 0.2389

GRAVY Index-0.08

Hydrophobic Moment 0.79

Boman Index0.03

Instability Index12.09

Aliphatic Index 108.11

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1609.25

LogP -11.84

H-bond Donors 55.0

H-bond Acceptors 53.0

Rotatable Bonds 142.0

Heavy Atoms 285.0

Ring Count 5.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314269 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetActive against Escherichia coli BL21