Peptide Database

Peptide NameHepcidin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC423H660N124O119S11

DescriptionStandard

        MKAFSVAFAMVLVLARTCIFSSYALPYSEKPEQERSSLVLEHQQVEDHSQNSFAATRVRRQSHLSLCRWCCKCCHNKGCGFCCKF
    

Molecular Weight9739.24 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)4.77

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0561

GRAVY Index-0.11

Hydrophobic Moment 0.54

Boman Index-0.04

Instability Index66.94

Aliphatic Index 65.41

Aromaticity 0.1059

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3930.80

LogP -41.56

H-bond Donors 148.0

H-bond Acceptors 139.0

Rotatable Bonds 322.0

Heavy Atoms 677.0

Ring Count 16.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120001 VERIFIED: NO

Provenance & Taxonomy

OrganismPlecoglossus altivelis [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0211669 VERIFIED: NO