Peptide Database

Peptide NameColicin-E2 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length534 amino acids

Chemical FormulaC2654H4124N732O803S13

DescriptionStandard

        MNDQTTQIYNLMRYEFAQVEGDFTSLRESDVKSVIPAGMRFADFLEQLRSGHQVLLTDAPSIPLLIRDRDEWGNQYWRVNPDIEPQLDGLAYKAYTARVALVNHGIGATYSGSVNASVSTEPHVEREPVKLTLAERLVRQRQERLQALDKIQLPSSSWQNAFNKPALKPEPKPQQVFAKSLFVPCGSCDIGTEREALTDMGQIAAYGAVAMNNTTALTGEVTFVEAGGSVLKSLSGLALRVAKVGLSPATAALALFMPSKLADGTLYDEENLRHMAVANTNIRLGFNPSGQIYGYHVKGAEIPVRHVEQVGEKFVVALESDHTLEWVPIQPEDKDSHLTTSPIPALDSYPIWIHPESGEAELTGTNEPYSTPIHQPDVKDYILTFPVESGLPALYVVYQENPRHESGVVTGYGEDITDQWLTTAGKELGAPVPSQIADKLRGCEFSNFDRFRKAFWLTVSEDENLMSQFNRHNQKKIRAGKAPFAPQNQKYGEIMRFEIHHVEEIQHGGAIYDVDNMRVVTPKNHKRIHYGDKQ
    

Molecular Weight59550.40 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-14.95

Net Charge (pH 7.4) -16.22

Charge Density (pH 7.0) -0.0280

GRAVY Index-0.42

Hydrophobic Moment 0.76

Boman Index0.00

Instability Index37.63

Aliphatic Index 81.82

Aromaticity 0.0843

Extinction Coeff. Reduced 66810.00

Extinction Coeff. Oxidized 66935.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081799 VERIFIED: NO

Provenance & Taxonomy

OrganismVibrio spartinae [Bacterium]

FamilyPyocin/Colicin

Tax ID1918945

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Hydrolase Non-hemolytic Non-ribosomal