Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC372H589N93O97S2

DescriptionStandard

        MLGKLLGLFTYLVGVTAISTDTAHKVFDMINAGATLASILGLIGASGGILGLSGAALWWFLKRKARQLGEEAFVAW
    

Molecular Weight7980.35 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)1.59

Net Charge (pH 7.4) 1.31

Charge Density (pH 7.0) 0.0209

GRAVY Index0.78

Hydrophobic Moment 0.69

Boman Index0.37

Instability Index20.27

Aliphatic Index 122.11

Aromaticity 0.1053

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2987.43

LogP -20.32

H-bond Donors 107.0

H-bond Acceptors 102.0

Rotatable Bonds 263.0

Heavy Atoms 564.0

Ring Count 12.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0253668 VERIFIED: NO

Provenance & Taxonomy

OrganismStaphylococcus rostri [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal