Peptide Database

Peptide NameNeurophysin 2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC404H646N124O135S15

DescriptionStandard

        AMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGVGFPRRV
    

Molecular Weight9881.18 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-3.32

Net Charge (pH 7.4) -3.73

Charge Density (pH 7.0) -0.0349

GRAVY Index-0.25

Hydrophobic Moment 0.67

Boman Index-0.02

Instability Index58.67

Aliphatic Index 51.37

Aromaticity 0.0421

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4101.95

LogP -55.11

H-bond Donors 152.0

H-bond Acceptors 147.0

Rotatable Bonds 319.0

Heavy Atoms 678.0

Ring Count 12.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174882 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familyvasopressin/oxytocin family

Tax ID9913; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-54; 13-27; 21-44; 28-34; 61-73; 67-85; 74-79

Bio-Activity Profile

Function

Hormone vasopressin oxytocin family

RECORD: Rec_0196672 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyVasopressin/oxytocin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-13

Bio-Activity Profile

Function

Neurohypophyseal hormone Neuropeptide

RECORD: Rec_0288324 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyNeurophysin

Tax ID9913

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-54; 13-27; 21-44; 28-34; 61-73; 67-85; 74-79

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasoconstrictor Receptor modulation

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour