Peptide Database

Peptide NameBeta-defensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC344H557N99O89S6

DescriptionStandard

        HRALTLTLVFPALLWGGRLITPILWLNNLAKSDSYICARKGGTCNLSPCPLYNRIEGTCYRGKAKCCIR
    

Molecular Weight7696.10 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)7.78

Net Charge (pH 7.4) 7.43

Charge Density (pH 7.0) 0.1128

GRAVY Index0.12

Hydrophobic Moment 0.52

Boman Index0.06

Instability Index37.58

Aliphatic Index 101.88

Aromaticity 0.0870

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3012.19

LogP -26.43

H-bond Donors 114.0

H-bond Acceptors 104.0

Rotatable Bonds 247.0

Heavy Atoms 538.0

Ring Count 13.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234311 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal