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MYP_041364
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Basic Information
Short α-helical peptides
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C80H154N20O15
Standard
Sequence
GIIKKIIKKIIKKI
Physicochemical Analysis
1636.20 Da
10.70
5.75
5.54
0.4110
0.55
0.87
0.08
-33.16
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
597.74
0.43
21.0
21.0
65.0
115.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0312841 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae ATCC 700603
8 μM
MIC
PaperHigh Therapeutic Index alpha-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections
RECORD: Rec_0327561 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm
C. krusei
12.5±2 μM
MIC
PMID34626966 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34626966/
RECORD: Rec_0331957 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii ATCC 19606
4 μM
MIC
PaperHigh Therapeutic Index alpha-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections
RECORD: Rec_0336857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm
Mature Candida albicans biofilm
PMID34626966 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34626966/
RECORD: Rec_0337398 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm
Initial Candida albicans biofilm
PMID34626966 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34626966/
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