‹ ›
MYP_041364
← PREVIOUS NEXT → BACK
Basic Information
Short α-helical peptides
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C80H154N20O15
Standard
Sequence
GIIKKIIKKIIKKI
Physicochemical Analysis
1636.20 Da
10.70
5.75
5.54
0.4110
0.55
0.87
0.08
-33.16
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
597.74
0.43
21.0
21.0
65.0
115.0
0.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0012449 VERIFIED: YES
Provenance & Taxonomy
Alpha-helical proteins [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa Approx
95 %
Cytotoxicity
PaperPubMed PMID: 24246647 PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0015359 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human erythrocytes
800 μM
HC50
PMID34626966 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34626966/
RECORD: Rec_0025801 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0047767 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
4 μM
MIC
PaperHigh Therapeutic Index alpha-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections
RECORD: Rec_0075718 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alpha-helical proteins
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
HL-60
5 μM
Cytotoxicity assay
PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
1 2 3 ... 5 NEXT LAST
Showing 5 records on this page · Page 1 of 5