Peptide Database

Peptide NameHepcidin1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC406H646N108O122S12

DescriptionStandard

        MKIFSVAVAVAVVLTFICIQESSAVPVAEELELEVPMIPDTPDAHGETSVDSWEMLYKSRQKRDARCRFCCGCCEPGICGVCCRF
    

Molecular Weight9376.90 Da

Isoelectric Point (pI)4.81

Net Charge (pH 7.0)-4.48

Net Charge (pH 7.4) -4.90

Charge Density (pH 7.0) -0.0527

GRAVY Index0.31

Hydrophobic Moment 0.38

Boman Index0.11

Instability Index30.02

Aliphatic Index 83.65

Aromaticity 0.0706

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3631.88

LogP -33.32

H-bond Donors 134.0

H-bond Acceptors 131.0

Rotatable Bonds 303.0

Heavy Atoms 648.0

Ring Count 13.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371069 VERIFIED: NO

Provenance & Taxonomy

OrganismChelon ramada [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal