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MYP_041269
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Basic Information
hepcidin TH1-5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C94H153N29O24S8
Standard
Sequence
GIKCRFCCGCCTPGICGVCCRF
Physicochemical Analysis
2329.92 Da
8.54
2.68
2.36
0.1218
1.00
0.33
0.18
12.79
48.64
0.0909
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
835.68
-9.68
38.0
35.0
72.0
155.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075121 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion of the African Frog,Kassina senegalensis [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
20 μg/mL
IC50
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32374
RECORD: Rec_0142485 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Tilapia, Oreochromis mossambicus
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
Colorectal Cancer (Not Available)
PMID17067680;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17067680/
RECORD: Rec_0151141 VERIFIED: YES
Provenance & Taxonomy
Skin Secretion of the African Frog,Kassina senegalensis [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32374
RECORD: Rec_0153025 VERIFIED: YES
Provenance & Taxonomy
Oreochromis mossambicus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Listeria monocytogenes
100 μg/mL
MIC
PaperThree different hepcidins from tilapia, Oreochromis mossambicus: analysis of their expressions and biological functions
RECORD: Rec_0183345 VERIFIED: YES
Provenance & Taxonomy
Oreochromis mossambicus [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral Anticancer
Enterococcus faecium
100 μg/mL
MIC
PaperThree different hepcidins from tilapia, Oreochromis mossambicus: analysis of their expressions and biological functions
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