Peptide Database

Peptide NamePhylloseptin-1 precursor

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC89H145N23O22

DescriptionStandard

        LSLIPHIVSGVASIAKHF
    

Molecular Weight1889.24 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.63

Charge Density (pH 7.0) 0.0519

GRAVY Index1.18

Hydrophobic Moment 0.51

Boman Index0.48

Instability Index21.78

Aliphatic Index 151.67

Aromaticity 0.0556

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 693.30

LogP -4.36

H-bond Donors 24.0

H-bond Acceptors 25.0

Rotatable Bonds 59.0

Heavy Atoms 134.0

Ring Count 4.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054636 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity5 μM

MethodMBEC

RECORD: Rec_0184417 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetAt the MIC/MBEC for Staphylococcus aureus

Activity5 μM

MethodHemolysis

RECORD: Rec_0263995 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagii [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity5 μM

MethodMIC

RECORD: Rec_0385306 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antibacterial Antimicrobial