Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC422H679N119O112S8

DescriptionStandard

        MKPNFLLSSATRIPVLLFTIFFFMSQVLPARGKFKEICERPNGSCRDFCLKTEIHVGRCLNSRPCCLPLGHQPRIESTTPKKD
    

Molecular Weight9468.16 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.63

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0798

GRAVY Index-0.13

Hydrophobic Moment 0.47

Boman Index-0.03

Instability Index50.92

Aliphatic Index 78.67

Aromaticity 0.0843

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3687.76

LogP -33.86

H-bond Donors 133.0

H-bond Acceptors 129.0

Rotatable Bonds 309.0

Heavy Atoms 661.0

Ring Count 17.0

Amide Bonds 87.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0387306 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence