Peptide Database

Peptide NamePleurocidin-like peptide GcSc4C5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC133H194N38O32

DescriptionStandard

        GWGSIFKHIFKAGKFIHGAIQAHNDG
    

Molecular Weight2837.20 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)2.02

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.0777

GRAVY Index-0.14

Hydrophobic Moment 0.70

Boman Index0.22

Instability Index15.78

Aliphatic Index 71.54

Aromaticity 0.1538

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1114.42

LogP -8.74

H-bond Donors 38.0

H-bond Acceptors 37.0

Rotatable Bonds 93.0

Heavy Atoms 203.0

Ring Count 8.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207589 VERIFIED: YES

Provenance & Taxonomy

OrganismGlyptocephalus cynoglossus [Animal]

FamilyPleurocidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetMRSA C623

Activity16 μg/mL

MethodMIC

RECORD: Rec_0218269 VERIFIED: YES

Provenance & Taxonomy

OrganismGlyptocephalus cynoglossus [Animal]

FamilyPleurocidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetAeromonas salmonicida 99-1

Activity32 μg/mL

MethodMIC

RECORD: Rec_0230856 VERIFIED: YES

Provenance & Taxonomy

OrganismGlyptocephalus cynoglossus [Animal]

FamilyPleurocidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetSalmonella enterica serovar Typhimurium 14028s

Activity64 μg/mL

MethodMIC

RECORD: Rec_0245294 VERIFIED: YES

Provenance & Taxonomy

OrganismGlyptocephalus cynoglossus [Animal]

FamilyPleurocidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa K799

Activity32 μg/mL

MethodMIC

RECORD: Rec_0256871 VERIFIED: YES

Provenance & Taxonomy

OrganismGlyptocephalus cynoglossus [Animal]

FamilyPleurocidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetSalmonella enterica serovar Typhimurium MS7953s

Activity16 μg/mL

MethodMIC

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