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MYP_041133
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Basic Information
R9
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C54H110N36O10
Standard
Sequence
RRRRRRRRR
Physicochemical Analysis
1423.69 Da
12.00
8.76
8.56
0.9733
-4.50
0.37
-2.53
518.04
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
853.22
-11.35
37.0
19.0
53.0
100.0
0.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0107406 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugation with TMR
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22465335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465335/
RECORD: Rec_0115103 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922[90-100% Inhibition = 20-30 microM
PMID22023266;24243601;26922474;20920465 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023266/
RECORD: Rec_0143324 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oligoarginine/Polycationic
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
Amidation
N-term detail: Fluorescein labelled; lowercase source residues at positions 1,2,3,4,5,6,7,8,9 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
Jurkat
Fluorescence-based uptake assay
PMID21867915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21867915/
RECORD: Rec_0168720 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperThe design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters PMID11087855 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087855/
RECORD: Rec_0173163 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
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