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MYP_041133
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Basic Information
R9
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C54H110N36O10
Standard
Sequence
RRRRRRRRR
Physicochemical Analysis
1423.69 Da
12.00
8.76
8.56
0.9733
-4.50
0.37
-2.53
518.04
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
853.22
-11.35
37.0
19.0
53.0
100.0
0.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000465 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923[60-70% Inhibition = 30 microM
PMID22023266;24243601;26922474;20920465 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023266/
RECORD: Rec_0002733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oligoarginine/Polycationic
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with aminohexanoic space; lowercase source residues at positions 1,2,3,4,5,6,7,8,9 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
Jurkat
Fluorescence-based uptake assay
PMID11087855 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087855/
RECORD: Rec_0002866 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Palustrin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio parahaemolyticus ISP 72-01[0-10% Inhibition = 10 microM
PMID22023266;24243601;26922474;20920465 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22023266/
RECORD: Rec_0008847 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oligoarginine
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Fluorescein labelled
Bio-Activity Profile
Cell-penetrating peptide
MC57
Fluorescence-based uptake assay
PMID21867915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21867915/
RECORD: Rec_0012735 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oligoarginine/Polycationic
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
Amidation
N-term detail: Fluorescein labelled; lowercase source residues at positions 1,2,3,4,5,6,7,8,9 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
MC57
Fluorescence-based uptake assay
PMID21867915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21867915/
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