Peptide Database

Peptide NameBradykinin-potentiating peptide 7a

Function Ontology

Cardiovascular

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Ion channel modulation

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC32H50N8O11

DescriptionStandard

        QDGPIPP
    

Molecular Weight722.79 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1770

GRAVY Index-1.10

Hydrophobic Moment 0.05

Boman Index0.07

Instability Index59.49

Aliphatic Index 55.71

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 291.94

LogP -2.76

H-bond Donors 7.0

H-bond Acceptors 10.0

Rotatable Bonds 17.0

Heavy Atoms 51.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294605 VERIFIED: YES

Provenance & Taxonomy

OrganismBothrops jararaca [Animal]

FamilyBradykinin-potentiating peptide 7a

Tax ID8724

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Bio-Activity Profile

Function

Cardiovascular Enzyme modulation Ion channel modulation Receptor modulation ACE inhibitory

Targetcoupled receptor

Activity0.25±0.31 μM

MethodEC50

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0370468 VERIFIED: YES