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MYP_041103
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Basic Information
Tesamorelin
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
44 amino acids
C215H357N71O67S
Standard
Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL
Physicochemical Analysis
5040.64 Da
10.40
3.76
3.55
0.0855
-0.80
0.61
-0.27
38.48
80.00
0.0682
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2330.50
-27.95
83.0
72.0
177.0
354.0
3.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034815 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Lipidation
Bio-Activity Profile
Hormone replacement
26 and 38 minutes in healthy subjects and HIV-infected patients, respectively.
Evidence URLhttps://patents.google.com/patent/US5861379 PatentUS5861379
RECORD: Rec_0069587 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Metabolic
PMID6812220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6812220/
RECORD: Rec_0149932 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Somatoliberin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation Sleep regulation Wake regulation
the adenohypophyse to stimulate the secretion of growth hormone
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Somatoliberin (Homo sapiens): PMID 6812220 PMID6812220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6812220/
RECORD: Rec_0182038 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0199897 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
GHRH analogue
9606;32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-Hexenoyl
Amidation
Lipidation (3-Hexenoyl)
Bio-Activity Profile
Growth hormone secretagogue Metabolic
Human GHRH receptor
Clinical/Human: 26 min (healthy subject), 38 min (HIV-infected patients)
Evidence URLhttps://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022505s000lbl.pdf
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