Peptide Database

Peptide NameCyclotide protein Mra22 (Fragment)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC448H745N123O145S7

DescriptionStandard

        LATFERDVITPETVHAILKKTNSNSNIMLHEDAIQALTGKTLISKTVLEEALLKNAENGLVGSGVPCGESCVWIPCLTSIVGCSCKNNVCTLNSLAQN
    

Molecular Weight10398.90 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-2.11

Net Charge (pH 7.4) -2.52

Charge Density (pH 7.0) -0.0215

GRAVY Index0.18

Hydrophobic Moment 0.49

Boman Index0.13

Instability Index28.04

Aliphatic Index 106.43

Aromaticity 0.0204

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4304.42

LogP -49.96

H-bond Donors 151.0

H-bond Acceptors 152.0

Rotatable Bonds 349.0

Heavy Atoms 723.0

Ring Count 8.0

Amide Bonds 108.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180282 VERIFIED: NO

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

ConfigBackbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0232885 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Tax ID344147

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial