Peptide Database

Peptide NameBrevinin-1GHa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC114H201N29O26S2

DescriptionStandard

        FLGAVLKVAGKLVPAAICKISKKC
    

Molecular Weight2458.12 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.50

Charge Density (pH 7.0) 0.1973

GRAVY Index1.05

Hydrophobic Moment 0.51

Boman Index0.28

Instability Index4.41

Aliphatic Index 134.17

Aromaticity 0.0417

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 874.16

LogP -4.66

H-bond Donors 32.0

H-bond Acceptors 33.0

Rotatable Bonds 84.0

Heavy Atoms 171.0

Ring Count 2.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377093 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct based on Sylvirana guentheri [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide18-24

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetKlebsiella pneumoniae

Activity8 μM

MethodMIC

RECORD: Rec_0409201 VERIFIED: YES