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MYP_041087
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Basic Information
Brevinin-1GHa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C114H201N29O26S2
Standard
Sequence
FLGAVLKVAGKLVPAAICKISKKC
Physicochemical Analysis
2458.12 Da
9.90
4.74
4.50
0.1973
1.05
0.51
0.28
4.41
134.17
0.0417
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
874.16
-4.66
32.0
33.0
84.0
171.0
2.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051684 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
16 μM
Hemolysis
PMID30322120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30322120/
RECORD: Rec_0058586 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Sylvirana guentheri [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus or MRSA
2-4 μM
MIC
PaperEvaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa From the Frog Skin Secretion of Hylarana guentheri and Its Analogues
RECORD: Rec_0073286 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae
PMID30322120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30322120/
RECORD: Rec_0088807 VERIFIED: YES
Provenance & Taxonomy
Hylarana guentheri [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis
PMID30322120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30322120/
RECORD: Rec_0164054 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Sylvirana guentheri [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
2 μM
MIC
PaperEvaluating the Bioactivity of a Novel Broad-Spectrum Antimicrobial Peptide Brevinin-1GHa From the Frog Skin Secretion of Hylarana guentheri and Its Analogues
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