Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC162H281N45O47S2

DescriptionStandard

        GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKISGGC
    

Molecular Weight3675.37 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1010

GRAVY Index0.56

Hydrophobic Moment 0.60

Boman Index0.22

Instability Index3.25

Aliphatic Index 115.68

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1488.51

LogP -16.49

H-bond Donors 53.0

H-bond Acceptors 53.0

Rotatable Bonds 129.0

Heavy Atoms 256.0

Ring Count 1.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413842 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyBrevinin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide31-37

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity30 μM

MethodMIC

FIRST PREV 1 2 3 4

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