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MYP_040968
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Basic Information
Pumilarin (46-70)[G2W,T5K,Q8K,Y9K], Syn-Safencin-P24
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C142H245N43O31
Standard
Sequence
AWKEKIRKKLKNEIKKKGRKAVIAW
Physicochemical Analysis
3050.73 Da
10.84
8.79
8.59
0.3517
-1.20
0.65
-0.42
0.32
86.00
0.0800
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1268.97
-6.69
46.0
40.0
114.0
216.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0256183 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae M6
128 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0280601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis NCTC 12201
128 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0336687 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human keratinocytes HaCat
64 μg/mL
Cytotoxicity
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0363905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas syringae pv. tomato
0.5 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0377295 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae NCTC 13368
128 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
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