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MYP_040944
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Basic Information
FLAK03 AM
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
23 amino acids
C126H232N32O24
Standard
Sequence
FALALKALKKLLKKLKKLAKKAL
Physicochemical Analysis
2579.39 Da
10.90
8.75
8.53
0.3805
0.31
0.84
-0.03
-16.27
157.39
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.70
-1.06
33.0
33.0
99.0
182.0
1.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0257360 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma H1299
72 μg/mL
LD50
PMID15980369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
RECORD: Rec_0257891 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
H-1299
72 μg/mL
LD50
PaperShort bioactive peptides Evidence URLhttps://patents.google.com/patent/US6875744B2/en PatentUS6875744B2
RECORD: Rec_0262458 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
FLAK / Hecate / Shiva peptide family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
HeLa
145.0 μg/mL
LD50 / MTT-MTS assay
PaperCancerPPD exact sequence record; FLAK03 AM PatentUS_06875744_B2
RECORD: Rec_0266436 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa PAO1
8 μg/mL
MIC
PMID15980369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
RECORD: Rec_0284647 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
40 μg/mL
MBC
PMID15980369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15980369/
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