Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC559H897N151O165S3

DescriptionStandard

        PDLNGHEKYGLGNVKYNISRIRVTAVEFPSASISLLPGTGIKLVIANASLTIDMNWSLRTWMFKDTGRSTVYISKIFVTAIFSKPPDHTGHTLISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12469.21 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)5.21

Net Charge (pH 7.4) 4.96

Charge Density (pH 7.0) 0.0457

GRAVY Index-0.04

Hydrophobic Moment 0.53

Boman Index0.09

Instability Index9.80

Aliphatic Index 94.91

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5061.13

LogP -53.39

H-bond Donors 182.0

H-bond Acceptors 176.0

Rotatable Bonds 411.0

Heavy Atoms 878.0

Ring Count 19.0

Amide Bonds 119.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0044461 VERIFIED: YES

Provenance & Taxonomy

OrganismNothoprocta ornata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria