Peptide Database

Peptide NameNatriuretic peptides A

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC116H191N37O39S2

DescriptionStandard

        SKSSSPCFGGKLDRIGSYSGLGCNSRK
    

Molecular Weight2792.11 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.1273

GRAVY Index-0.68

Hydrophobic Moment 0.51

Boman Index-0.16

Instability Index40.00

Aliphatic Index 43.33

Aromaticity 0.0741

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1255.22

LogP -19.94

H-bond Donors 48.0

H-bond Acceptors 45.0

Rotatable Bonds 95.0

Heavy Atoms 194.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304180 VERIFIED: YES

Provenance & Taxonomy

OrganismAnguilla japonica [Animal]

FamilyNatriuretic peptides

Tax ID7937

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-23

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0413123 VERIFIED: NO