Peptide Database

Peptide NameLysin (EC 3.5.1.28) (Cell wall hydrolase) (Lytic amidase) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Protease

Enzyme / Catalytic activity ▸ Protease ▸ Thiol protease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length296 amino acids

Chemical FormulaC1566H2221N403O459S13

DescriptionStandard

        MGVDIEKGVAWMQARKGRVSYSMDFRDGPDSYDCSSSMYYALRSAGASSAGWAVNTEYMHAWLIENGYELISENAPWDAKRGDIFIWGRKGASAGAGGHTGMFIDSDNIIHCNYAYDGISVNDHDERWYYAGQPYYYVYRLTNANAQPAEKKLGWQKDATGFWYARANGTYPKDEFEYIEENKSWFYFDDQGYMLAEKWLKHTDGNWYWFDRDGYMATSWKRIGESWYYFNRDGSMVTGWIKYYDNWYYCDATNGDMKSNAFIRYNDGWYLLLPDGRLADKPQFTVEPDGLITAKV
    

Molecular Weight34452.66 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-11.07

Net Charge (pH 7.4) -11.69

Charge Density (pH 7.0) -0.0374

GRAVY Index-0.71

Hydrophobic Moment 0.61

Boman Index-0.01

Instability Index41.03

Aliphatic Index 52.20

Aromaticity 0.1926

Extinction Coeff. Reduced 136710.00

Extinction Coeff. Oxidized 136835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188852 VERIFIED: YES

Provenance & Taxonomy

OrganismPneumococcus phage Dp-1 [Virus]

FamilyPeptidase C40

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Protease Thiol protease Non-hemolytic

TargetNo Target Organism Found

RECORD: Rec_0205210 VERIFIED: NO