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MYP_040892
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Basic Information
E50,51TAT-Cd0
Antimicrobial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Standard
11 amino acids
C56H104N30O17S
Standard
Sequence
GREERRQRRRC
Physicochemical Analysis
1501.68 Da
11.70
3.76
3.54
0.3414
-3.22
0.56
-1.52
212.45
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
843.41
-11.62
34.0
22.0
55.0
104.0
0.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0229343 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
Herpes simplex virus type 1(HSV-1):inhibition of viral infection in human corneal epithelial (HCE) cells
EC50
PaperPubMed PMID: 21029018 PMID21029018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21029018/
RECORD: Rec_0279174 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Anti-HSV Infection inhibition
Herpes simplex virus type 1(HSV-1)
30 μM
EC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperA cationic TAT peptide inhibits Herpes simplex virus type 1 infection of human corneal epithelial cells. | Larsen IV, Brandt CR. | J Ocul Pharmacol Ther. 2010 Dec;26(6):541-7. | DOI:10.1089/jop.2010.0076 | PMID:21029018 PMID21029018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21029018/
RECORD: Rec_0322225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 21029018 PMID21029018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21029018/