Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length113 amino acids

Chemical FormulaC537H869N147O162S4

DescriptionStandard

        DLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPMSISLTSCRTASGDIDIKLNGKS
    

Molecular Weight12104.79 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.02

Net Charge (pH 7.4) 2.63

Charge Density (pH 7.0) 0.0267

GRAVY Index0.09

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index23.30

Aliphatic Index 98.32

Aromaticity 0.0619

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4940.50

LogP -54.81

H-bond Donors 175.0

H-bond Acceptors 172.0

Rotatable Bonds 402.0

Heavy Atoms 850.0

Ring Count 16.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311579 VERIFIED: NO

Provenance & Taxonomy

OrganismOriolus oriolus (Eurasian golden oriole) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria