Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC450H737N137O142S9

DescriptionStandard

        MKCATIVCTIAVVLAATLLNGSVQAAPQEEAALSGGANLNTLLDELPEETHHAALENYRAKRATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
    

Molecular Weight10627.08 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.19

Charge Density (pH 7.0) 0.0068

GRAVY Index0.18

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index32.87

Aliphatic Index 91.08

Aromaticity 0.0392

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4466.91

LogP -54.67

H-bond Donors 164.0

H-bond Acceptors 155.0

Rotatable Bonds 349.0

Heavy Atoms 738.0

Ring Count 9.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357487 VERIFIED: YES

Provenance & Taxonomy

OrganismAnopheles gambiae [Animal]

FamilyDefensin

Tax ID7165

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-positive Hemolytic

TargetGram Positive Bacteria