Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC423H697N125O123S8

DescriptionStandard

        MKLLFLLLALLLATEPVASGECWMDGHCRLVCKNDEDSISRCRNRKRCCVPSRYLTIQPVTVDGILGWTTAQTPTPATTKKTNRNHV
    

Molecular Weight9758.34 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.62

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0531

GRAVY Index-0.17

Hydrophobic Moment 0.52

Boman Index-0.04

Instability Index46.45

Aliphatic Index 88.51

Aromaticity 0.0460

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3997.40

LogP -41.72

H-bond Donors 147.0

H-bond Acceptors 138.0

Rotatable Bonds 319.0

Heavy Atoms 679.0

Ring Count 13.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423959 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence