Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC387H601N93O107S9

DescriptionStandard

        CFFPISTVKCAMKDTFNCFLKKGKCRQSCHYFEEPVGFCTKLNAYCCVAVLQGVIYLNVKLIEDSETEIQAYLLV
    

Molecular Weight8557.06 Da

Isoelectric Point (pI)7.68

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.38

Charge Density (pH 7.0) 0.0103

GRAVY Index0.33

Hydrophobic Moment 0.55

Boman Index0.15

Instability Index62.98

Aliphatic Index 89.60

Aromaticity 0.1333

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3214.03

LogP -23.87

H-bond Donors 117.0

H-bond Acceptors 118.0

Rotatable Bonds 282.0

Heavy Atoms 596.0

Ring Count 13.0

Amide Bonds 80.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0041383 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic