Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2302H3623N613O653S8

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGISILEKELAQLKLPDMSGDSRVGRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFDLKVENVYIKISLKLGSDATGKPTVSTWECSARISKVRVLFSGSLGWLYNLFHGAIESRFRKILEDKICDIVDKSVQNELQKFVQTLPVTARIDAKTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHEAGALVFEITEDMIPKDVGFSLDTSTFSAFIPQLEEMYPNMPVKFRLSTPTAPFLTIGPGGISLKPIVEAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRYRGEQPLTGQGVASVRTIQSLMNILTSSSLLPRLNARLDEGFPLPLLDRIQLFNILVRFYQNFLLLGADVHFQPQ
    

Molecular Weight50590.63 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)4.12

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.0090

GRAVY Index0.05

Hydrophobic Moment 0.67

Boman Index0.10

Instability Index33.33

Aliphatic Index 101.75

Aromaticity 0.0987

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421466 VERIFIED: NO

Provenance & Taxonomy

OrganismAphelocoma coerulescens (Florida scrub-jay) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria