Peptide Database

Peptide NameSLAY-screened peptide P2982

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC71H119N23O23

DescriptionStandard

        IRFSSPRIRITDSD
    

Molecular Weight1662.84 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0547

GRAVY Index-0.64

Hydrophobic Moment 0.36

Boman Index-0.32

Instability Index62.80

Aliphatic Index 83.57

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 774.05

LogP -9.32

H-bond Donors 29.0

H-bond Acceptors 24.0

Rotatable Bonds 54.0

Heavy Atoms 117.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272540 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/