Peptide Database

Peptide NamePiscidin-4, ecPis-4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length54 amino acids

Chemical FormulaC284H429N91O73S

DescriptionStandard

        FFRHIKSFWKGAKAIFRGARQGWREHRALSKQRKMDQGGGGNEVDNGTPPYWQK
    

Molecular Weight6318.08 Da

Isoelectric Point (pI)11.04

Net Charge (pH 7.0)7.94

Net Charge (pH 7.4) 7.62

Charge Density (pH 7.0) 0.1469

GRAVY Index-1.24

Hydrophobic Moment 0.90

Boman Index-0.26

Instability Index28.32

Aliphatic Index 34.44

Aromaticity 0.1481

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2708.95

LogP -26.98

H-bond Donors 96.0

H-bond Acceptors 84.0

Rotatable Bonds 212.0

Heavy Atoms 449.0

Ring Count 15.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312349 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyPiscidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal

TargetStaphylococcus aureus

Activity5 μM

MethodMBC

RECORD: Rec_0366393 VERIFIED: YES