MYP_040729
Tirzepatide
Hormonal / Endocrine
▸
Hormone peptide
Metabolic
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Glucose metabolism
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not Standard
39 amino acids
-
contains X representing unresolved or non-standard residue
YXEGTFTSDYSIXLDKIAQKAFVQWLIAGGPSSGAPPPS
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0218398
VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Insulin
32630
Structure & Mods
linear peptide/protein therapeutic [Linear]
noncanonical stereochemical or chemical modification [Modified]
Ambiguous/noncanonical residue symbol X present in deposited sequence
Bio-Activity Profile
Hormone replacement
,The half-life is approximately five days.
RECORD: Rec_0400054
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; synthetic construct [Synthetic]
GIP/GLP-1 dual agonist
9606;32630
Structure & Mods
branched peptide architecture [Branched]
mixed L/D amino-acid peptide [Mixed]
Amidation
Non-standard residues/X at 2, 13; Lipidation
Bio-Activity Profile
Antidiabetic
Weight management
GIP receptor agonist
GLP-1 receptor agonist
Human GIP receptor and GLP-1 receptor
Clinical/Human: Approximately 5 d