Peptide Database

Peptide NameGuanylate-binding protein 5 (EC 3.6.5.-) (GBP-TA antigen) (GTP-binding protein 5) (GBP-5) (Guanine nucleotide-binding protein 5)

Function Ontology

Antimicrobial

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length586 amino acids

Chemical FormulaC2940H4699N807O906S24

DescriptionStandard

        MALEIHMSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFSVASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTSEREAIEVFMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEEAVKQGIYSKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQMEIAKQNWLAEQQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNNDDPCVLL
    

Molecular Weight66616.18 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-16.35

Net Charge (pH 7.4) -17.55

Charge Density (pH 7.0) -0.0279

GRAVY Index-0.45

Hydrophobic Moment 0.73

Boman Index-0.05

Instability Index37.23

Aliphatic Index 90.22

Aromaticity 0.0648

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 46005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174634 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Hydrolase Non-hemolytic

TargetNo Target Organism Found