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MYP_040611
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Basic Information
Basic phospholipase A2 homolog BmajPLA2-II (svPLA2 homolog)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxin
not Standard
106 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
NLWQLGKMILLETGKIPAKSYGAYGCNCGVLGRCCYVHKXXXXKLTGCDPKXXXYSYSWKXXTIVCGENNSCLKELCECDKAVAICLRENLDTYNKXXXYNYLKPF
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070227 VERIFIED: YES
Provenance & Taxonomy
Bothrops marajoensis [Animal]
Phospholipase A2; Group II subfamily; K49 sub-subfamily
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Undefined residue X at positions 40-43, 52-54, 61-62, 97-99
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Toxin Non-hemolytic
Trypanosoma cruzi
PMID28390830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28390830/
RECORD: Rec_0110242 VERIFIED: YES
Provenance & Taxonomy
Bothrops marajoensis [Animal]
Phospholipase A2; Group II subfamily; K49 sub-subfamily
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Undefined residue X at positions 40-43, 52-54, 61-62, 97-99
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Toxin Non-hemolytic
Escherichia coli (Gram-negative)
PMID28390830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28390830/
RECORD: Rec_0145875 VERIFIED: YES
Provenance & Taxonomy
Bothrops marajoensis [Animal]
Phospholipase A2; Group II subfamily; K49 sub-subfamily
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Undefined residue X at positions 40-43, 52-54, 61-62, 97-99
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Toxin Non-hemolytic
Leishmania infantum
PMID28390830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28390830/
RECORD: Rec_0194352 VERIFIED: YES
Provenance & Taxonomy
Bothrops marajoensis [Animal]
Phospholipase A2; Group II subfamily; K49 sub-subfamily
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Undefined residue X at positions 40-43, 52-54, 61-62, 97-99
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Antiparasitic Anti-Gram-negative Toxin Non-hemolytic
Candida albicans
PMID28390830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28390830/