Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length235 amino acids

Chemical FormulaC1205H1815N271O359S9

DescriptionStandard

        VDDLAEIDYSLSSLPAVFQPFIDLDLKGTVFPAGNYTGSPYVVAPFTITDQRDSMLFLAFSEYFFQTSSFAYYTAGAFNMTIAEEVSQTHLFSLFYFFFQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNVFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight26130.49 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-16.08

Net Charge (pH 7.4) -16.47

Charge Density (pH 7.0) -0.0684

GRAVY Index0.39

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index44.72

Aliphatic Index 95.83

Aromaticity 0.1447

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135352 VERIFIED: YES

Provenance & Taxonomy

OrganismManacus vitellinus [Animal]

FamilyBPI/LBP

Tax ID328815

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria