Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC160H269N53O50S4

DescriptionStandard

        NTLQRYYCRIRSGRCALLSCLPKEEQIGRCSSTG
    

Molecular Weight3863.43 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.1095

GRAVY Index-0.53

Hydrophobic Moment 0.60

Boman Index-0.24

Instability Index70.47

Aliphatic Index 71.76

Aromaticity 0.0588

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1716.06

LogP -21.98

H-bond Donors 67.0

H-bond Acceptors 58.0

Rotatable Bonds 130.0

Heavy Atoms 267.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247858 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)