Peptide Database

Peptide NameConotoxin TxO1

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC121H179N25O34S6

DescriptionStandard

        CLDAGEVCDIFFPTCCGYCILLFCA
    

Molecular Weight2720.25 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.30

Net Charge (pH 7.4) -3.59

Charge Density (pH 7.0) -0.1318

GRAVY Index1.47

Hydrophobic Moment 0.31

Boman Index0.49

Instability Index34.00

Aliphatic Index 97.60

Aromaticity 0.1600

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 905.29

LogP -4.82

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 81.0

Heavy Atoms 186.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046196 VERIFIED: NO

Provenance & Taxonomy

OrganismConus textile [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0262258 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 16.0%, E 0.0%, T 44.0%, C 40.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic