Peptide Database

Peptide Name[D-Trp12]PTH-(7-34) (bovine)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC165H250N48O40S2

DescriptionStandard

        FMHNLWKHLSSMERVEWLRKKLQDVHNF
    

Molecular Weight3610.18 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.0723

GRAVY Index-0.78

Hydrophobic Moment 0.61

Boman Index-0.15

Instability Index78.39

Aliphatic Index 76.43

Aromaticity 0.1429

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1450.13

LogP -8.56

H-bond Donors 51.0

H-bond Acceptors 47.0

Rotatable Bonds 122.0

Heavy Atoms 255.0

Ring Count 9.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263625 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetPTH2 receptor (Human); PTH2 receptor (Rat)