MYP_040515
White cloud bean defensin
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibacterial
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Anti-Mycobacterium
Antimicrobial
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Antifungal
Antiviral
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Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Toxicity / Safety
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Negative safety assay result
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Non-hemolytic
Venom / Toxin
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General toxin
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Cytotoxic
Standard
75 amino acids
C372H579N109O108S11
Standard
MEKKSFAGLCFLFLVLFVAQECVLQTEAKTCENLADTFRGPCFATGNCDDHCKNKEHLLRGRCRDDFRCWCTRNC
8658.96 Da
7.49
0.59
0.11
0.0079
-0.25
0.63
-0.10
31.84
59.87
0.1067
5500.00
6125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3535.50
-36.00
133.0
122.0
289.0
600.0
12.0
80.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0397116
VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
Knottin
3885
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anticancer
Cytotoxic
Botrytis cinerea
2.8±0.01 μM
IC50
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