Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC421H674N116O124S14

DescriptionStandard

        MKTFSVAVVAAVLLALICLQESSALPLSEVEDVEVPVMDDNGAAVYEEMPVDSWKMPYTNRHKRSPKRCKFCCNCCPGMRGCGGVCCRF
    

Molecular Weight9793.47 Da

Isoelectric Point (pI)6.53

Net Charge (pH 7.0)-0.49

Net Charge (pH 7.4) -0.91

Charge Density (pH 7.0) -0.0055

GRAVY Index0.12

Hydrophobic Moment 0.61

Boman Index0.05

Instability Index70.72

Aliphatic Index 74.38

Aromaticity 0.0674

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3803.11

LogP -36.96

H-bond Donors 139.0

H-bond Acceptors 139.0

Rotatable Bonds 317.0

Heavy Atoms 675.0

Ring Count 14.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069812 VERIFIED: NO

Provenance & Taxonomy

OrganismTakifugu flavidus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal