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MYP_040461
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Basic Information
Alyteserin-1Ma
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
23 amino acids
C106H177N29O30
Standard
Sequence
GFKEVLKADLGSLVKGIAAHVAN
Physicochemical Analysis
2337.72 Da
8.51
0.85
0.59
0.0369
0.48
0.40
0.24
-16.68
123.04
0.0435
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
948.18
-8.01
32.0
32.0
80.0
165.0
2.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000455 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
400 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
RECORD: Rec_0064518 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0108762 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
214 μM
MIC
RECORD: Rec_0127677 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
214 μM
MIC
RECORD: Rec_0169360 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides (https://pubmed.ncbi.nlm.nih.gov/22325123/) PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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