Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length486 amino acids

Chemical FormulaC2449H3883N641O691S23

DescriptionStandard

        MTSCVLSLYFLLSLCSSISADGPTGLKVRITDRAPDVLKSFGQAYLKELIGKPFPDFQFKGMKMAKCKIKGLTVNHLDVDRDKVVVRFQQDSGLQFEFRDLNFTAELQREINVRGKIVDEGTVNVTGKGVRATIGVRLNQNQGRLSLKIQNCDVHADKIAMKFHQGLGPVLNRFKKEFQHLFKTKVCPAIKRHAVPKVNSMLANVTMAMSLSEDLGMNLDYSLSGEVTVTPSSLDVPFTGVVYHGDIRPALPAAGVQPVFTESNLMAYVGISEDLFKSAAQALYSHGPLQLDVPQIGTIPNYVLHTWGLPEGRVEVELTEVPDITISQDGLSVYVKAIAQSLVNPDLPHLPMTCQVLINVDMEGCRLILQALSSKCKIEPKTIWGRFLATFVDTSSKISSFIEEWFDEGVLIPLPDRLDFTQMKINYYPGFMVVGGDLTYTVQRAVLRSIHPSPTIAIDPGSSRKFQSFLFLILLILYIWFCKRCF
    

Molecular Weight54099.40 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)4.32

Net Charge (pH 7.4) 3.33

Charge Density (pH 7.0) 0.0089

GRAVY Index0.08

Hydrophobic Moment 0.77

Boman Index0.11

Instability Index29.35

Aliphatic Index 99.61

Aromaticity 0.0885

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 40505.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363869 VERIFIED: NO

Provenance & Taxonomy

OrganismPerca fluviatilis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria