Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC345H558N102O82S7

DescriptionStandard

        MKPFVLTLAALLLLSQLTPGGSQKCWNLKGRCRHRCFKKERIYVFCTNNKPCCVKPRFQPRERLF
    

Molecular Weight7671.21 Da

Isoelectric Point (pI)10.26

Net Charge (pH 7.0)11.53

Net Charge (pH 7.4) 11.16

Charge Density (pH 7.0) 0.1773

GRAVY Index-0.30

Hydrophobic Moment 0.44

Boman Index-0.13

Instability Index24.96

Aliphatic Index 76.46

Aromaticity 0.1077

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2996.20

LogP -24.47

H-bond Donors 111.0

H-bond Acceptors 102.0

Rotatable Bonds 254.0

Heavy Atoms 536.0

Ring Count 14.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328819 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinolophus ferrumequinum [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

PaperThe Genome 10K Project: a way forward; Bat Biology, Genomes, and the Bat1K Project: To Generate Chromosome-Level Genomes for All Living Bat Species; Six reference-quality genomes reveal evolution of bat adaptations PMID25689317;29166127;32699395 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/?term=25689317+OR+29166127+OR+32699395